Organ‐on‐a‐Chip Systems for Women's Health Applications
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700550
Abstract: Biomedical research, for a long time, has paid little attention to the influence of sex in many areas of study, ranging from molecular and cellular biology to animal models and clinical studies on human subjects.… read more here.
Keywords: chip systems; physiology; women health; organ chip ... See more keywords
Field‐Programmable Topographic‐Morphing Array for General‐Purpose Lab‐on‐a‐Chip Systems
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202410604
Abstract: Lab‐on‐a‐chip systems seek to leverage microfluidic chips to enable small‐scale fluid manipulation, holding significant potential to revolutionize science and industry. However, existing microfluidic chips have been largely designed with static fluid structures for specific single‐purpose… read more here.
Keywords: field; purpose; chip systems; lab chip ... See more keywords
Mechanobiological stimulation in organ‐on‐a‐chip systems reduces hepatic drug metabolic capacity in favor of regenerative specialization
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28653
Abstract: Hepatic physiology depends on the liver's complex structural composition which among others, provides high oxygen supply rates, locally differential oxygen tension, endothelial paracrine signaling, as well as residual hemodynamic shear stress to resident hepatocytes. While… read more here.
Keywords: drug metabolic; chip systems; culture; drug ... See more keywords
Nanofluidic Lab-On-A-Chip Systems for Biosensing in Healthcare.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202407478
Abstract: Biosensing plays a vital role in healthcare monitoring, disease detection, and treatment planning. In recent years, nanofluidic technology has been increasingly explored to be developed into lab-on-a-chip biosensing systems. Given now the possibility of fabricating… read more here.
Keywords: lab; analysis; chip systems; lab chip ... See more keywords
An Impedance Sensing Platform for Monitoring Heterogeneous Connectivity and Diagnostics in Lab-on-a-Chip Systems
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b04048
Abstract: Reliable hardware connectivity is vital in heterogeneous integrated systems. For example, in digital microfluidics lab-on-a-chip systems, there are hundreds of physical connections required between a microelectromechanical fabricated device and the driving system that can be… read more here.
Keywords: chip systems; connectivity; impedance sensing; sensing platform ... See more keywords
Engineering organ-on-a-chip systems to model viral infections
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac6538
Abstract: Infectious diseases remain a public healthcare concern worldwide. Amidst the pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 infection, increasing resources have been diverted to investigate therapeutics targeting the… read more here.
Keywords: engineering organ; model viral; organ chip; viral infections ... See more keywords
Lab-on-a-Chip Systems for Aptamer-Based Biosensing
Sign Up to like & getrecommendations! Published in 2020 at "Micromachines"
DOI: 10.3390/mi11020220
Abstract: Aptamers are oligonucleotides or peptides that are selected from a pool of random sequences that exhibit high affinity toward a specific biomolecular species of interest. Therefore, they are ideal for use as recognition elements and… read more here.
Keywords: chip systems; aptamer based; systems aptamer; based biosensing ... See more keywords
Advancing Organ-on-a-Chip Systems: The Role of Scaffold Materials and Coatings in Engineering Cell Microenvironment
Sign Up to like & getrecommendations! Published in 2025 at "Polymers"
DOI: 10.3390/polym17091263
Abstract: For organ-on-a-chip (OoC) engineering, the use of biocompatible coatings and materials is not only recommended but essential. Extracellular matrix (ECM) components are commonly used as coatings due to their effects on cell orientation, protein expression,… read more here.
Keywords: engineering; chip systems; cell; advancing organ ... See more keywords