Identification of the differential and synergic lipotoxic patterns of oleic acid, palmitic acid, and their mixture in 3D HepG2/C3A tissue using liver-on-chip technology.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology progress"
DOI: 10.1002/btpr.70075
Abstract: The metabolic dysfunction-associated steatotic liver disease (MASLD, previously formerly known as non-alcoholic fatty liver disease, NAFLD) is rapidly expanding worldwide in parrallel with the obesity pandemic. Dietary fatty acids including oleic (OA) and palmitic acids… read more here.
Keywords: hepg2 c3a; chip technology; hepg2;
Fabrication of a novel porous silicon biomembrane for applications in organ-on-chip technology
Sign Up to like & getrecommendations! Published in 2025 at "Biomedical Microdevices"
DOI: 10.1007/s10544-025-00760-3
Abstract: Conventional in vitro and preclinical animal models often fail to accurately replicate the complexity of human diseases, limiting the success of translational studies and contributing to the low success rate of clinical trials (Ingber 2016).… read more here.
Keywords: porous silicon; chip technology; chip; organ chip ... See more keywords
Application of microfluidic chip technology in pharmaceutical analysis: A review
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2018.12.001
Abstract: The development of pharmaceutical analytical methods represents one of the most significant aspects of drug development. Recent advances in microfabrication and microfluidics could provide new approaches for drug analysis, including drug screening, active testing and… read more here.
Keywords: microfluidic chip; analysis; pharmaceutical analysis; chip technology ... See more keywords
Recent Advances in Additive Manufacturing and 3D Bioprinting for Organs-On-A-Chip and Microphysiological Systems
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.837087
Abstract: The re-creation of physiological cellular microenvironments that truly resemble complex in vivo architectures is the key aspect in the development of advanced in vitro organotypic tissue constructs. Among others, organ-on-a-chip technology has been increasingly used… read more here.
Keywords: tissue; organ chip; additive manufacturing; chip ... See more keywords
Organ-on-Chip Technology: Current State and Future Developments
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DOI: 10.3390/genes8100266
Abstract: In the early days of pharmacy, the development of new drugs was frequently achieved by restless chemists who worked solitarily, day by day for years [...]. read more here.
Keywords: future developments; organ chip; current state; technology current ... See more keywords
Enhancing Endothelial Differentiation of Mesenchymal Stem Cells Derived from Human Turbinates Using Lab-on-a-Chip Technology
Sign Up to like & getrecommendations! Published in 2025 at "Medicina"
DOI: 10.3390/medicina61030528
Abstract: Background and Objectives: Endothelial cells are essential to various therapeutic strategies for cardiovascular diseases. Developing efficient methods to generate large quantities of well-defined endothelial cells could improve cardiovascular treatment. This study explored the impact of… read more here.
Keywords: lab chip; endothelial differentiation; chip; chip technology ... See more keywords
Physiological and Disease Models of Respiratory System Based on Organ-on-a-Chip Technology
Sign Up to like & getrecommendations! Published in 2021 at "Micromachines"
DOI: 10.3390/mi12091106
Abstract: The pathogenesis of respiratory diseases is complex, and its occurrence and development also involve a series of pathological processes. The present research methods are have difficulty simulating the natural developing state of the disease in… read more here.
Keywords: based organ; organ chip; chip technology; respiratory ... See more keywords