Chiral Phosphoric Acid-Catalyzed Asymmetric Arylation of Indolizines: Atroposelective Access to Axially Chiral 3-Arylindolizines.
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DOI: 10.1021/acs.orglett.2c00461
Abstract: We report herein a highly straightforward strategy for the synthesis of a new axially chiral 3-arylindolizine scaffold via organocatalytic asymmetric arylation reactions of indolizines and p-quinone esters. Using the chiral phosphoric acid catalyst, a series… read more here.
Keywords: asymmetric arylation; chiral phosphoric; chiral arylindolizines; phosphoric acid ... See more keywords