Asymmetric Retro-Claisen Reaction Catalyzed by Chiral Aza-Bisoxazoline-Zn(II) Complex: Enantioselective Synthesis of α-Arylated Ketones.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00372
Abstract: An asymmetric retro-Claisen reaction of α-monosubstituted β-diketones and quinones (or quinone imine) has been developed under the catalysis of a chiral aza-bisoxazoline-Zn(II) complex. The reaction proceeds via a sequence of conjugate addition, arylation, hemiketal anion-initiated… read more here.
Keywords: aza bisoxazoline; asymmetric retro; reaction; claisen reaction ... See more keywords
Constructing chiral aza-quaternary carbon centers by enantioselective carbonylative Heck reaction of o-iodoanilines with allenes
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01486a
Abstract: The construction of chiral aza-quaternary carbon centers via C–N bond formation has been achieved by a palladium-catalyzed asymmetric carbonylative Heck reaction of o-iodoanilines with allenes, providing chiral dihydroquinolinone derivatives with moderate to high yield and… read more here.
Keywords: chiral aza; aza quaternary; carbon centers; quaternary carbon ... See more keywords