Enantioselective Syntheses of Tricyclic Benzimidazoles via Intramolecular Allylic Aminations with Chiral-Bridged Biphenyl Phosphoramidite Ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03640
Abstract: The first iridium-catalyzed enantioselective intramolecular allylic aminations of benzimidazole-tethered allylic carbonates were developed, providing three classes of tricyclic benzimidazoles bearing a tertiary carbon stereogenic center in high yields and excellent enantioselectivities (up to 99% yield,… read more here.
Keywords: tricyclic benzimidazoles; allylic aminations; chiral bridged; enantioselective syntheses ... See more keywords
Asymmetric organocatalyzed reaction sequence of 2-hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines to construct diverse chiral bridged polycyclic aminals
Sign Up to like & getrecommendations! Published in 2019 at "Organic Chemistry Frontiers"
DOI: 10.1039/c9qo01116a
Abstract: 2-Hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines were used as multisite substrates in an iminium catalysis triggered sequential process, leading to diverse chiral bridged polycyclic aminals in a highly regio- and stereoselective manner. read more here.
Keywords: cinnamaldehydes acyclic; diverse chiral; chiral bridged; acyclic sulfonyl ... See more keywords