Transition‐Metal‐Catalyzed Construction of Axially Chiral Carbonyl Compounds
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DOI: 10.1002/ejoc.202400995
Abstract: The synthesis of axially chiral carbonyl compounds has attracted considerable interest in organic synthesis due to their prevalence in natural products and pharmaceuticals, as well as their utility in material science and catalysis. Transition‐metal‐catalyzed approaches… read more here.
Keywords: metal catalyzed; transition metal; axially chiral; chiral carbonyl ... See more keywords
Synthesis of chiral α-carbonyl-δ-nitro-ketenedithioacetals via l-proline-catalyzed Michael addition reaction
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DOI: 10.1007/s11164-017-3025-1
Abstract: Regioselective synthesis of 1,1-bis(methylthio)-6-nitro-5-arylhex-1-en-3-one has been achieved from α-alkenoylketene dithioacetals with nitromethane using l-proline catalyst via Michael addition. The synthesized compounds 3a–j were well characterised by NMR and mass spectral techniques. One of the structures… read more here.
Keywords: nitro ketenedithioacetals; addition; synthesis chiral; michael addition ... See more keywords