A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib.
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DOI: 10.1002/chir.23485
Abstract: Acalabrutinib is aided in the treatment of various cancers, which acts by inhibiting Bruton tyrosine kinase. Acalabrutinib belongs to the imidazopyrazine class consisting of a chiral carbon, resulting in two enantiomers. Currently, no methods exist… read more here.
Keywords: validated chiral; acalabrutinib; chromatographic method; chiral chromatographic ... See more keywords