Advances and challenges in the pharmacokinetics and bioanalysis of chiral drugs.
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DOI: 10.1002/chir.23495
Abstract: Enantioselective analytical approaches are essential for monitoring pharmacokinetics and acquiring accurate data to better understand the role of stereochemistry in pharmacokinetics. Enantioselectivity significantly impacts the pharmacokinetics of chiral drugs, especially in metabolic profile, leading to… read more here.
Keywords: challenges pharmacokinetics; pharmacokinetics bioanalysis; bioanalysis chiral; advances challenges ... See more keywords
Biocatalysis: A smart and green tool for the preparation of chiral drugs
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DOI: 10.1002/chir.23498
Abstract: Abstract Over the last decades, biocatalysis has achieved growing interest thanks to its potential to enable high efficiency, high yield, and eco‐friendly processes aimed at the production of pharmacologically relevant compounds. Particularly, biocatalysis proved an… read more here.
Keywords: biocatalysis smart; preparation chiral; chiral drugs; tool preparation ... See more keywords