Chiral β-lactam-based integrin ligands through Lipase-catalysed kinetic resolution and their enantioselective receptor response.
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DOI: 10.1016/j.bioorg.2019.102975
Abstract: Obtainment and testing of pure enantiomers are of great importance for bioactive compounds, because of the assessed implications of enantioselectivity in receptor-mediated responses. Herein we evaluated the use of biocatalysis to obtain enantiomerically pure β-lactam… read more here.
Keywords: receptor; kinetic resolution; integrin ligands; chiral lactam ... See more keywords