Synthesis of chiral γ-lactones via a RuPHOX-Ru catalyzed asymmetric hydrogenation of aroylacrylic acids
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.05.036
Abstract: Abstract An asymmetric hydrogenation of aroylacrylic acids catalyzed by RuPHOX-Ru catalyst has been developed, affording the corresponding chiral γ-lactones in high yields and with up to 93% ee. The methodology has the advantage of utilizing… read more here.
Keywords: aroylacrylic acids; asymmetric hydrogenation; hydrogenation aroylacrylic; synthesis chiral ... See more keywords
Ni-Catalyzed Asymmetric Hydrogenation of Aromatic Ketoacids for the Synthesis of Chiral Lactones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00608
Abstract: A highly efficient Ni-catalyzed asymmetric hydrogenation of aromatic γ- and δ-ketoacids has been developed, affording a series of γ- and δ-aryl lactones in high yields and excellent enantioselectivities (≤98% ee). The hydrogenation could occur smoothly… read more here.
Keywords: aromatic ketoacids; hydrogenation; asymmetric hydrogenation; catalyzed asymmetric ... See more keywords
Highly efficient and enantioselective synthesis of chiral lactones via Ir-catalysed asymmetric hydrogenation of ketoesters.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02069f
Abstract: Owing to the biological significance and great synthetic value of chiral lactones and their derivatives, increasing attention has been paid to developing effective synthetic methods for chiral lactones. We herein report an efficient asymmetric hydrogenation… read more here.
Keywords: enantioselective synthesis; highly efficient; asymmetric hydrogenation; efficient enantioselective ... See more keywords