Enantioseparation of 3-phenyllactic acid by chiral ligand exchange countercurrent chromatography.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201601384
Abstract: 3-Phenyllactic acid is an antimicrobial compound with broad-spectrum activity against various bacteria and fungus. The observed difference in pharmacological activity between optical isomeric 3-phenyllactic acid necessitates a method for enantioseparation. Chiral ligand exchange countercurrent chromatography… read more here.
Keywords: phenyllactic acid; countercurrent chromatography; chiral ligand;
Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of separation science"
DOI: 10.1002/jssc.201701117
Abstract: This work deals with the enantioseparation of α-amino acids by chiral ligand exchange high-speed countercurrent chromatography using N-n-dodecyl-l-hydroxyproline as a chiral ligand and copper(II) as a transition metal ion. A biphasic solvent system composed of… read more here.
Keywords: chromatography; amino acids; enantioseparation amino; countercurrent chromatography ... See more keywords
Asymmetric Synthesis of α-Alkylidene-β-Lactams through Copper Catalysis with a Prolinol-Phosphine Chiral Ligand.
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DOI: 10.1021/acs.orglett.9b00276
Abstract: A copper/prolinol-phosphine chiral catalyst enabled the one-step synthesis of chiral α-alkylidene-β-lactams. Optimization of the chiral ligand for steric and electronic properties realized the highly enantioselective coupling of nitrones and propargyl alcohol derived alkynes. The resulting… read more here.
Keywords: phosphine chiral; alkylidene; alkylidene lactams; prolinol phosphine ... See more keywords