Enantioselective C(sp2)–H borylation of diarylmethylsilanes catalyzed by chiral pyridine-dihydroisoquinoline iridium complexes
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DOI: 10.1016/j.tet.2020.131811
Abstract: Abstract Enantioselective C(sp2)−H borylations of diarylmethylsilanes were catalyzed using iridium complexes with chiral pyridine-dihydroisoquinoline (PyDHIQ) ligands. High enantioselectivities (up to >99% ee) were observed for various substrates. A gram-scale synthesis was achieved using 1 mol%… read more here.
Keywords: chiral pyridine; pyridine dihydroisoquinoline; iridium complexes; enantioselective sp2 ... See more keywords
Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A
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DOI: 10.3390/molecules25051096
Abstract: A series of branched tetrapeptide Schiff bases 3–6 were designed and synthesized from corresponding tetrapeptide hydrazide 2 as a starting material.In vitroevaluation of the synthesized compounds 4–6 against breast MCF-7 carcinoma cells identified their excellent… read more here.
Keywords: chiral pyridine; bis phenylalaninyl; pyridine bis; docking studies ... See more keywords