A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
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DOI: 10.1038/s41467-017-02204-w
Abstract: D-aminoacyl-tRNA deacylase (DTD), a bacterial/eukaryotic trans-editing factor, removes d-amino acids mischarged on tRNAs and achiral glycine mischarged on tRNAAla. An invariant cross-subunit Gly-cisPro motif forms the mechanistic basis of l-amino acid rejection from the catalytic… read more here.
Keywords: dtd; relaxed paralog; selectivity relaxed; trna ... See more keywords
Co-crystallization of racemic amino acids with ZnCl2: an investigation of chiral selectivity upon coordination to the metal centre
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DOI: 10.1039/d0ce00775g
Abstract: The amino acids alanine, valine, proline, isoleucine, serine, asparagine, tyrosine, and threonine in their racemic forms have been reacted with ZnCl2 under different preparative conditions (grinding and LAG, both manual and ball milling, and co-crystallization… read more here.
Keywords: selectivity upon; coordination; amino; amino acids ... See more keywords
Principles of chemical geometry underlying chiral selectivity in RNA minihelix aminoacylation
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky909
Abstract: Abstract The origin of homochirality in L-amino acid in proteins is one of the mysteries of the evolution of life. Experimental studies show that a non-enzymatic aminoacylation reaction of an RNA minihelix has a preference… read more here.
Keywords: rna minihelix; rna; geometry; aminoacylation ... See more keywords