Enantioselective CE–MS analysis of ketamine metabolites in urine
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202200175
Abstract: The chiral drug ketamine has long‐lasting antidepressant effects with a fast onset and is also suitable to treat patients with therapy‐resistant depression. The metabolite hydroxynorketamine (HNK) plays an important role in the antidepressant mechanism of… read more here.
Keywords: ketamine metabolites; ketamine; enantioselective analysis; chiral selector ... See more keywords
Enantioseparation of pheniramine enantiomers by high-speed countercurrent chromatography using β-cyclodextrin derivatives as a chiral selector.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700345
Abstract: The enantioselective separation of pheniramine was studied by a high-speed countercurrent chromatography method using β-cyclodextrin derivatives as a chiral selector. Several key variables, for instance, type of organic solvent and chiral selector, concentration of chiral… read more here.
Keywords: chromatography; chiral selector; speed countercurrent; countercurrent chromatography ... See more keywords
Development of a capillary electrophoretic method for determination of ketorolac enantiomers in human plasma using cationic β-cyclodextrin derivative as a chiral selector.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200601
Abstract: A novel approach for separation of ketorolac enantiomers by CE is presented. Cationic β-cyclodextrin derivative based on imidazole was synthesized and used as a chiral selector in background electrolyte. The influence of pH and ionic… read more here.
Keywords: cyclodextrin derivative; human plasma; chiral selector; ketorolac ... See more keywords
Chiral separation of methadone using solid membrane extraction based on chiral selector, solid membrane: sheep skin leather
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-019-01634-1
Abstract: A new, green, and without solvent extraction method and chiral separation system effective in separation of racemic methadone is presented. We have used sheep leather as the membrane in enantioselective extraction for chiral separation of… read more here.
Keywords: chiral selector; methadone; separation; membrane ... See more keywords
Powerful Steroid-Based Chiral Selector for High-Throughput Enantiomeric Separation of α-Amino Acids Utilizing Ion Mobility-Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02691
Abstract: Stereospecific recognition of amino acids (AAs) plays a crucial role in chiral biomarker-based diagnosis and prognosis. Separation of AA enantiomers is a long and tedious task due to the requirement of AA derivatization prior to… read more here.
Keywords: amino acids; chiral selector; mass; separation ... See more keywords
L-Histidinium Chiral Ionic Liquid Functionalized β-Cyclodextrin as Chiral Selector in Capillary Electrophoresis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmaa115
Abstract: Nowadays, ionic liquids (ILs) functionalized cyclodextrins (CDs) have drawn increasing attention in chiral separation. Herein, a novel β-CD derivative functionalized by L-histidinium IL, mono-6-deoxy-6-L-histidinium-β-cyclodextrin chloride (L-HMCDCl), was synthesized for the first time and utilized for… read more here.
Keywords: chiral selector; capillary electrophoresis; histidinium; histidinium chiral ... See more keywords
Human Serum Albumin as Chiral Selector in Enantioselective High-Performance Liquid Chromatography.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666161118115711
Abstract: Enantioselective high-performance liquid chromatography (eHPLC) using chiral stationary phases (CSPs) is surely the most used technique for the determination of the enantiomeric excess (e.e.) of chiral drugs, a fundamental parameter for reliable studies on the… read more here.
Keywords: chiral selector; enantioselective high; performance; high performance ... See more keywords