Articles with "chiral separation" as a keyword



Chiral separation materials based on derivatives of 6-amino-6-deoxyamylose.

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Published in 2021 at "Chirality"

DOI: 10.1002/chir.23368

Abstract: In order to develop new type of chiral separation materials, in this study, 6-amino-6-deoxyamylose was used as chiral starting material with which 10 derivatives were synthesized. The amino group in 6-amino-6-deoxyamylose was selectively acylated and… read more here.

Keywords: separation materials; deoxy bis; chiral separation; css ... See more keywords

Chiral separation of calcium channel antagonists by SFC and HPLC using different immobilized chiral stationary phases.

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Published in 2022 at "Chirality"

DOI: 10.1002/chir.23410

Abstract: Supercritical fluid chromatography and high-performance liquid chromatography techniques are popular for the chiral separations of different drugs and pharmaceuticals. Therefore, this article describes a comparative study of the chiral separation of some calcium channel antagonists… read more here.

Keywords: separation calcium; channel antagonists; calcium channel; chiral separation ... See more keywords

Chiral separation of β-blockers by supercritical fluid chromatography using Chiralpak-IG and Chiralpak IBN-5 columns.

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Published in 2022 at "Chirality"

DOI: 10.1002/chir.23440

Abstract: Chiral separation of β-blockers is performed by utilizing the supercritical fluid chromatographic method. The chiral columns utilized were Chiralpak IG and Chiralpak IBN-5. The finest mobile phase was CO2 -0.2% TEA in methanol (60:40). The… read more here.

Keywords: separation blockers; chiralpak ibn; chiral separation; supercritical fluid ... See more keywords

Metal-organic frameworks in chiral separation of pharmaceuticals.

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Published in 2022 at "Chirality"

DOI: 10.1002/chir.23499

Abstract: Stereoselective chiral molecules are responsible for specific biological functions in nature. At present, more than half of the prescribed drugs are chiral. Living organisms display divergent pharmacological responses to the enantiomers, leading to altered toxicity,… read more here.

Keywords: organic frameworks; chiral separation; metal organic; separation ... See more keywords

Enantiomeric separation of tryptophan via novel chiral polyamide composite membrane.

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Published in 2024 at "Chirality"

DOI: 10.1002/chir.23674

Abstract: The separation of chiral drugs continues to pose a significant challenge. However, in recent years, the emergence of membrane-based chiral separation has shown promising effectiveness due to its environmentally friendly, energy-efficient, and cost-effective characteristics. In… read more here.

Keywords: separation; chiral separation; composite membrane; tryptophan ... See more keywords
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Chiral Separation via Molecular Sieving: A Computational Screening of Suitable Functionalizations for Nanoporous Graphene

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Published in 2018 at "Chemphyschem"

DOI: 10.1002/cphc.201800413

Abstract: Abstract In a recent study [Angew. Chem. Int. Ed., 2014, 53, 9957–9960] a new concept of chiral separation has been suggested, which is based on functionalized, nanoporous sheets of graphene. In this follow‐up article we discuss… read more here.

Keywords: sieving computational; chiral separation; via molecular; separation ... See more keywords

Chiral separation of lansoprazole and rabeprazole by capillary electrophoresis using dual cyclodextrin systems

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Published in 2019 at "ELECTROPHORESIS"

DOI: 10.1002/elps.201900107

Abstract: Novel capillary electrophoresis methods using CDs as chiral selectors were developed and validated for the chiral separation of lansoprazole and rabeprazole, two proton pump inhibitors. Fourteen different neutral and anionic CDs were screened at pH… read more here.

Keywords: capillary electrophoresis; separation lansoprazole; chiral separation; lansoprazole rabeprazole ... See more keywords
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Chiral separation of quinolones by liquid chromatography and capillary electrophoresis.

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Published in 2017 at "Journal of separation science"

DOI: 10.1002/jssc.201700200

Abstract: The quinolones are derivatives of oxoquinolines and mostly known for their antibacterial and antiviral activities. Many quinolones are chiral compounds having asymmetric centers and important due to their enantioselective biological activities. In order to study… read more here.

Keywords: chiral separation; separation; chromatography capillary; liquid chromatography ... See more keywords

Thermoresponsive PEG-Coated Nanotubes as Chiral Selectors of Amino Acids and Peptides.

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Published in 2018 at "Small"

DOI: 10.1002/smll.201800030

Abstract: A series of nanotubes with a dense layer of short poly(ethylene glycol) (PEG) chains on the inner surface are prepared by means of a coassembly process using glycolipids and PEG derivatives. Dehydration of the PEG… read more here.

Keywords: peg chains; nanotube channels; amino acids; chiral separation ... See more keywords

Chiral separation effect for spin 3/2 fermions

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Published in 2021 at "Journal of High Energy Physics"

DOI: 10.1007/jhep07(2021)183

Abstract: Abstract Chiral Separation Effect (CSE) for systems that feature spin 3/2 fermions was considered. For the self-consistent Adler’s model with relativistic massless Rarita-Schwinger fermions (RSA model), we found that the CSE conductivity is five times… read more here.

Keywords: separation effect; chiral separation; cse conductivity; spin fermions ... See more keywords

Chiral separation of (±)-methamphetamine racemate using molecularly imprinted sulfonic acid functionalized resin.

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Published in 2018 at "Journal of colloid and interface science"

DOI: 10.1016/j.jcis.2018.07.070

Abstract: In the present study, a sulfonic acid functionalized enantio-selective resinous material was developed for effective chiral separation of (±)-methamphetamine racemate. R-methamphetamine-sulfonamide phenolic derivative was first prepared and fully characterized utilizing instrumental and spectroscopic techniques, then… read more here.

Keywords: acid functionalized; methamphetamine; chiral separation; separation ... See more keywords