Atroposelective Synthesis of Axially Chiral Styrenes via an Asymmetric C–H Functionalization Strategy
Sign Up to like & getrecommendations! Published in 2020 at "Chem"
DOI: 10.1016/j.chempr.2019.12.011
Abstract: Summary Axially chiral styrenes, which exhibit a chiral axis between a substituted alkene and an aromatic ring, have been largely overlooked. The hurdle is the lower barriers to rotation compared with that of their biaryl… read more here.
Keywords: chiral styrenes; functionalization strategy; axially chiral; atroposelective synthesis ... See more keywords
Atroposelective Synthesis of Axially Chiral Styrenes Connecting an Axially Chiral Naphthyl-indole Moiety Using Chiral Phosphoric Acid Catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00425
Abstract: The organocatalytic asymmetric reactions of C2-unsubstituted racemic naphthyl-indoles with orthoalkynylnaphthols were employed to synthesize axially chiral styrenes connected to an axially chiral naphthyl-indole unit. Utilizing chiral phosphoric acid as the catalyst, these axially chiral styrenes… read more here.
Keywords: chiral styrenes; chiral phosphoric; chiral naphthyl; phosphoric acid ... See more keywords