Asymmetric rhodium-catalyzed click cycloaddition to access C–N axially chiral N-triazolyl indoles
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DOI: 10.1039/d3sc00610g
Abstract: The copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is regarded as a prime example of “click chemistry”, but the asymmetric click cycloaddition of internal alkynes still remains challenging. A new asymmetric Rh-catalyzed click cycloaddition of N-alkynylindoles with… read more here.
Keywords: catalyzed click; click cycloaddition; axially chiral; chiral triazolyl ... See more keywords