Articles with "chirality conversion" as a keyword



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A Central-to-Axial Chirality Conversion Strategy for the Synthesis of C-N Axially Chiral N-Arylpyrroles.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c00753

Abstract: We present a central-to-axial chirality conversion strategy for the construction of C-N axially chiral N-arylpyrroles via a gold(I)-catalyzed 5-endo-dig cyclization/dehydration cascade from amino acid derivatives. The reaction exhibits high efficiency on the central-to-axial chirality conversion.… read more here.

Keywords: axial chirality; conversion strategy; chirality conversion; central axial ... See more keywords