Chitinase1 contributed to a potential protection via microglia polarization and Aβ oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments
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DOI: 10.1016/j.neuroscience.2017.04.050
Abstract: Chitinase activity is increased in Alzheimer's disease (AD). However, the role of chitinase1 in AD is unknown. We investigated the effects of chitinase1 on Alzheimer's pathology and microglia function. Artificial chitinase1 and chitinase inhibitor (chitinase-IN-2)… read more here.
Keywords: model cognitive; cognitive impairments; induced rat; galactose alcl3 ... See more keywords