Injectable Biodegradable Chitosan-Alginate 3D Porous Gel Scaffold for mRNA Vaccine Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800242
Abstract: mRNA vaccines have proven to be more stable, effective, and specific than protein/peptide-based vaccines in stimulating both humoral and cellular immune response. However, mRNA's fast degradation rate and low-transfection efficiency in vivo impede its potential… read more here.
Keywords: delivery; vaccine; chitosan alginate; scaffold mrna ... See more keywords
Strategies for neurotrophin‐3 and chondroitinase ABC release from freeze‐cast chitosan–alginate nerve‐guidance scaffolds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1912
Abstract: Freeze casting, or controlled unidirectional solidification, can be used to fabricate chitosan–alginate (C–A) scaffolds with highly aligned porosity that are suitable for use as nerve‐guidance channels. To augment the guidance of growth across a spinal… read more here.
Keywords: nerve guidance; neurotrophin chondroitinase; guidance; chondroitinase abc ... See more keywords
Fibro/chondrogenic differentiation of dental stem cells into chitosan/alginate scaffolds towards temporomandibular joint disc regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-018-6109-6
Abstract: AbstractTissue engineering (TE) may provide effective alternative treatment for challenging temporomandibular joint (TMJ) pathologies associated with disc malpositioning or degeneration and leading to severe masticatory dysfunction. Aim of this study was to evaluate the potential… read more here.
Keywords: temporomandibular joint; chondrogenic differentiation; differentiation dental; fibro chondrogenic ... See more keywords
An overview on antimicrobial and wound healing properties of ZnO nanobiofilms, hydrogels, and bionanocomposites based on cellulose, chitosan, and alginate polymers.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115349
Abstract: Release of Zn2+ ions from zinc oxide nanoparticles (ZnO NPs) is a major mechanism for oligodynamic activities of these metal oxide NPs against eukaryotic and prokaryotic microorganisms. In addition to this mechanism, ZnO NPs can… read more here.
Keywords: wound healing; cellulose chitosan; zno nps; alginate polymers ... See more keywords
Pyrene biodegradation with layer-by-layer assembly bio-microcapsules.
Sign Up to like & getrecommendations! Published in 2017 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2016.11.019
Abstract: Biotechnology is considered as a promising technology for the removal of polycyclic aromatic hydrocarbons from the environment. Free bacteria are often sensitive to some biotic and abiotic factors in the environment to the extent that… read more here.
Keywords: biodegradation; layer layer; layer; bio microcapsules ... See more keywords
Characterization of nisin containing chitosan-alginate microparticles
Sign Up to like & getrecommendations! Published in 2017 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2017.02.011
Abstract: Abstract Nisin is a naturally occurring bacteriocin that has GRAS status for use in foods granted by the FDA. Encapsulation of nisin within microparticles can protect it from interactions with other food components, thereby increasing… read more here.
Keywords: alginate; characterization nisin; alginate microparticles; nisin containing ... See more keywords
Enhancing the functionality of chitosan- and alginate-based active edible coatings/films for the preservation of fruits and vegetables: A review.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.07.083
Abstract: A number of studies have established the potential of chitosan and alginate-based edible film/coatings for preserving the quality attributes of fruits and vegetables. Findings demonstrate that these films/coatings act as a barrier on the surface… read more here.
Keywords: alginate based; shelf life; chitosan alginate; fruits vegetables ... See more keywords
Synbiotic loaded chitosan-Ca-alginate microparticles reduces inflammation in the TNBS model of rat colitis.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.05.049
Abstract: New therapeutic strategies against inflammatory bowel disease (IBD) consider the usage of probiotics, prebiotics and synbiotics as beneficial for the intestinal microbial balance. Limitations of such an approach are addressed into difference in survival, persistence,… read more here.
Keywords: rat colitis; model rat; loaded chitosan; alginate microparticles ... See more keywords
Chitosan alginate nanoparticles as a platform for the treatment of diabetic and non-diabetic pressure ulcers: formulation and in vitro/in vivo evaluation.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120963
Abstract: Chitosan and alginate are natural bioactive polymers with wound healing properties, in addition to chitosan's anti-bacterial properties. In this study, these two polymers were combined in a drug-free nanosystem with positive or negative surface charges,… read more here.
Keywords: diabetic pressure; pressure ulcers; chitosan alginate; non diabetic ... See more keywords
Folic acid-chitosan-alginate nanocomplexes for multiple delivery of chemotherapeutic agents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.06.020
Abstract: Abstract A major challenge faced by researchers involved in the sphere of drug delivery is the development of innovative multidrug delivery systems. Herein, experimentation focused on preparing nanocomplexes based on chitosan and alginic acid with… read more here.
Keywords: folic acid; delivery; drug; acid chitosan ... See more keywords
Chitosan-alginate core-shell-corona shaped nanoparticles of dimethyl fumarate in orodispersible film to improve bioavailability in treatment of multiple sclerosis: Preparation, characterization and biodistribution in rats
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102645
Abstract: Abstract Dimethyl fumarate (DMF) is used for the treatment of relapsing forms of multiple sclerosis and causes undesired adverse effects in patients such as gastroenteritis, dyspepsia, low bioavailability, gastritis, nausea and flushing. The aim of… read more here.
Keywords: bioavailability; drug; alginate core; chitosan alginate ... See more keywords