Enhancing proteasome‐inhibitory activity and specificity of bortezomib by CD38 targeted nanoparticles in multiple myeloma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.11.045
Abstract: Abstract The establishment of more effective treatments that can circumvent chemoresistance in Multiple Myeloma (MM) is a priority. Although bortezomib (BTZ) is one of the most potent proteasome inhibitors available, still possesses limitations related to… read more here.
Keywords: cd38; multiple myeloma; proteasome inhibitory; cd38 targeted ... See more keywords
Progresses in targeted drug delivery systems using chitosan nanoparticles in cancer therapy: A mini-review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101813
Abstract: Abstract Chitosan, de-acetylated form of chitin and the amino polysaccharide, is one of the most suitable biopolymer with vast possibilities of chemical modifications for novel properties and nano-medicine generations in biomedical fields. The primary amine… read more here.
Keywords: drug delivery; chitosan nanoparticles; delivery; drug ... See more keywords
Adjuvant Activity of Poly-ε-caprolactone/Chitosan Nanoparticles Characterized by Mast Cell Activation and IFN-γ and IL-17 Production.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00730
Abstract: Polymeric nanoparticles (NPs) are extremely attractive vaccine adjuvants, able to promote antigen delivery and in some instances, exert intrinsic immunostimulatory properties that enhance antigen specific humoral and cellular immune responses. The poly-ε-caprolactone (PCL)/chitosan NPs were… read more here.
Keywords: cell activation; poly caprolactone; mast cell; chitosan nps ... See more keywords
Incorporation of Chitosan Nanoparticles into a Cold-Cure Orthodontic Acrylic Resin: Effects on Mechanical Properties
Sign Up to like & getrecommendations! Published in 2021 at "Biomimetics"
DOI: 10.3390/biomimetics6010007
Abstract: Improvement of the antibacterial properties of acrylic resins, used in the construction of removable orthodontic appliances, is an important strategy to reduce the incidence of caries and oral diseases in orthodontic treatments. The addition of… read more here.
Keywords: resin; strength; effects mechanical; acrylic resin ... See more keywords
Chitosan Nanoparticles at the Biological Interface: Implications for Drug Delivery
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DOI: 10.3390/pharmaceutics13101686
Abstract: The unique properties of chitosan make it a useful choice for various nanoparticulate drug delivery applications. Although chitosan is biocompatible and enables cellular uptake, its interactions at cellular and systemic levels need to be studied… read more here.
Keywords: drug delivery; chitosan nanoparticles; delivery; chitosan ... See more keywords
Formulation Development, Characterization and Antifungal Evaluation of Chitosan NPs for Topical Delivery of Voriconazole In Vitro and Ex Vivo
Sign Up to like & getrecommendations! Published in 2021 at "Polymers"
DOI: 10.3390/polym14010135
Abstract: This study aims to develop chitosan-based voriconazole nanoparticles (NPs) using spray-drying technique. The effect of surfactants and polymers on the physicochemical properties, in vitro release, and permeation of NPs was investigated. The prepared NPs containing… read more here.
Keywords: voriconazole; release; vitro release; chitosan nps ... See more keywords