PARP activity fine-tunes the DNA replication choreography of Chk1-depleted cells.
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DOI: 10.1016/j.jmb.2021.166949
Abstract: Checkpoint Kinase 1 (Chk1) prevents DNA damage by adjusting the replication choreography in the face of replication stress. Chk1 depletion provokes slow and asymmetrical fork movement, yet the signals governing such changes remain unclear. We… read more here.
Keywords: chk1; replication choreography; fork; chk1 depleted ... See more keywords