Articles with "chk2 gene" as a keyword



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Computational analysis of high-risk SNPs in human CHK2 gene responsible for hereditary breast cancer: A functional and structural impact

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0220711

Abstract: Nowadays CHK2 mutation is studied frequently in hereditary breast and ovarian cancer patients in addition to BRCA1/BRCA2. CHK2 is a tumor suppressor gene that encodes a serine/threonine kinase, also involved in pathways such as DNA… read more here.

Keywords: risk; breast; chk2 gene; chk2 ... See more keywords