Articles with "chk2 p53" as a keyword



Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway

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Published in 2017 at "Investigational New Drugs"

DOI: 10.1007/s10637-017-0552-y

Abstract: SummaryWe investigated the anti-tumour effects and the underlying molecular mechanisms of a new oral histone deacetylase inhibitor (HDACi), chidamide, in NK/T cell lymphoma (NKTCL), a rare and highly aggressive non-Hodgkin lymphoma with poor outcomes. SNT-8… read more here.

Keywords: p53 p21; chidamide; lymphoma; chk2 p53 ... See more keywords