The Chlamydia trachomatis p‐aminobenzoate synthase CADD is a manganese‐dependent oxygenase that uses its own amino acid residues as substrates
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14573
Abstract: CADD (chlamydia protein associating with death domains) is a p‐aminobenzoate (pAB) synthase involved in a noncanonical route for tetrahydrofolate biosynthesis in Chlamydia trachomatis. Although previously implicated to employ a diiron cofactor, here, we show that pAB… read more here.
Keywords: synthase; aminobenzoate synthase; chlamydia trachomatis; acid ... See more keywords
Sublingual Boosting with a Novel Mucoadhesive Thermogelling Hydrogel Following Parenteral CAF01 Priming as a Strategy Against Chlamydia trachomatis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102508
Abstract: Chlamydia trachomatis is the most prevalent sexually transmitted disease of bacterial origin. The high number of asymptomatic cases makes it difficult to stop the transmission, requiring vaccine development. Herein, a strategy is proposed to obtain… read more here.
Keywords: trachomatis; chlamydia; chlamydia trachomatis; sublingual boosting ... See more keywords
Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, and Neisseria gonorrhoeae in gynecological outpatients, Taizhou, China
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23072
Abstract: Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), and Neisseria gonorrhoeae (NG) are highly prevalent worldwide and may lead to some genital diseases. The objective of this large‐scale study was to estimate the prevalence characteristics of UU,… read more here.
Keywords: ureaplasma urealyticum; urealyticum chlamydia; chlamydia trachomatis; neisseria gonorrhoeae ... See more keywords
Structures of glyceraldehyde 3‐phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis
Sign Up to like & getrecommendations! Published in 2020 at "Protein Science"
DOI: 10.1002/pro.3824
Abstract: Neisseria gonorrhoeae (Ng) and Chlamydia trachomatis (Ct) are the most commonly reported sexually transmitted bacteria worldwide and usually present as co‐infections. Increasing resistance of Ng to currently recommended dual therapy of azithromycin and ceftriaxone presents… read more here.
Keywords: glyceraldehyde phosphate; phosphate dehydrogenase; neisseria gonorrhoeae; gonorrhoeae chlamydia ... See more keywords
One Face of Chlamydia trachomatis: The Infectious Elementary Body.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2016_12
Abstract: The lifestyle of Chlamydiae is unique: the bacteria alternate between two morphologically distinct forms, an infectious non-replicative elementary body (EB), and a replicative, non-infectious reticulate body (RB). This review focuses on recent advances in understanding… read more here.
Keywords: chlamydia trachomatis; one face; elementary body; body ... See more keywords
Whole-Genome Enrichment Using RNA Probes and Sequencing of Chlamydia trachomatis Directly from Clinical Samples.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7037-7_1
Abstract: Whole-genome sequencing is a powerful, high-resolution tool that can be used to generate accurate data on bacterial population structure, phylogeography, and mutations associated with antimicrobial resistance. The ability to sequence pathogen genomes directly from clinical… read more here.
Keywords: directly clinical; whole genome; chlamydia trachomatis; trachomatis ... See more keywords
Effects of iota-carrageenan on ocular Chlamydia trachomatis infection in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-018-1435-0
Abstract: Ocular chlamydial infections with the ocular serovars A, B, Ba, and C of Chlamydia trachomatis represent the world’s leading cause of infectious blindness. Carrageenans are naturally occurring, sulfated polysaccharides generally considered safe for food and… read more here.
Keywords: vivo; iota carrageenan; infection; pathology ... See more keywords
Chlamydia trachomatis Infections in a Tertiary Care Portuguese Hospital: An 11-Year Retrospective Study.
Sign Up to like & getrecommendations! Published in 2021 at "Actas dermo-sifiliograficas"
DOI: 10.1016/j.adengl.2021.03.001
Abstract: BACKGROUND Chlamydia trachomatis infections remain a burden worldwide. The goals of this study were to determine the number of C. trachomatis infections per year, characterize the demographic traits of the infected population and identify the… read more here.
Keywords: trachomatis infections; infection; chlamydia trachomatis; year ... See more keywords
A novel protease inhibitor causes inclusion vacuole reduction and disrupts the intracellular growth of Chlamydia trachomatis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.05.184
Abstract: Chlamydia (C.) trachomatis, characterized by a unique biphasic life cycle, is an obligate intracellular bacterial pathogen which is responsible for the highest number of sexually transmitted bacterial infections globally. However, its pathogenic mechanisms have not… read more here.
Keywords: inhibitor; protease; developmental cycle; chlamydia trachomatis ... See more keywords
In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Journal"
DOI: 10.1016/j.bj.2018.04.007
Abstract: Background Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane protein D (PmpD) is an attractive… read more here.
Keywords: cell epitopes; affinity; epitopes pmpd; chlamydia trachomatis ... See more keywords
Assessment and utility of 2 Chlamydia trachomatis Pgp3 serological assays for seroprevalence studies among women in the United States.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2021.115480
Abstract: Two plasmid gene protein (Pgp3)-based serological assays, the Pgp3-ELISA and multiplex bead assay (Pgp3-MBA), were compared and used to estimate seropositivity of Chlamydia trachomatis (CT) among females 14 to 39 years old participating in the… read more here.
Keywords: pgp3 elisa; serological assays; pgp3 mba; chlamydia trachomatis ... See more keywords