While home chlorhexidine washes prior to shoulder surgery lower skin loads of most bacteria, they are not effective against Cutibacterium (Propionibacterium)
Sign Up to like & getrecommendations! Published in 2020 at "International Orthopaedics"
DOI: 10.1007/s00264-019-04477-w
Abstract: Chlorhexidine showers prior to shoulder arthroplasty are commonly recommended by surgeons to lower the risk of periprosthetic infection; however, the effectiveness of these washes in eliminating bacteria from the skin of the shoulder has not… read more here.
Keywords: surgery; skin; shoulder; chlorhexidine ... See more keywords
Early periodontal wound healing after chlorhexidine rinsing: a randomized clinical trial
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-024-05643-0
Abstract: This single-center randomized, parallel design, clinical trial with a 2-week follow-up involved patients affected by periodontitis undergoing periodontal surgery. The aim was to evaluate periodontal surgical wound healing with the use of chlorhexidine-based mouth rinses… read more here.
Keywords: wound healing; chlorhexidine; periodontal surgery; chx ads ... See more keywords
Evaluation of degradation mechanism of chlorhexidine by means of Density Functional Theory calculations
Sign Up to like & getrecommendations! Published in 2017 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2017.10.001
Abstract: Chlorhexidine (CHD), a germicidal drug, has degradation products that can be hemotoxic and carcinogenic. However, there is no consensus in literature about the degradation pathway. In order to shed light on that mechanism, we have… read more here.
Keywords: degradation; density functional; mechanism; chlorhexidine ... See more keywords
Serratia marcescens outbreak due to contaminated 2% aqueous chlorhexidine.
Sign Up to like & getrecommendations! Published in 2017 at "Enfermedades Infecciosas Y Microbiologia Clinica"
DOI: 10.1016/j.eimce.2017.11.006
Abstract: Abstract Introduction and objective An outbreak of Serratia marcescens infections outbreak is described, as well as the epidemiological study that linked the outbreak to the use of 2% aqueous chlorhexidine antiseptic. Method In late November… read more here.
Keywords: aqueous chlorhexidine; epidemiological study; marcescens outbreak; chlorhexidine ... See more keywords
Antiseptic chlorhexidine in activated sludge: Biosorption, antimicrobial susceptibility, and alteration of community structure.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of environmental management"
DOI: 10.1016/j.jenvman.2019.02.043
Abstract: Chlorhexidine (CHX) is a broad-spectrum antimicrobial, which may pose environmental health risks. This study examined the removal potential and the mechanisms regulating the fate of CHX in activated sludge (AS). Bioreactors inoculated with AS removed… read more here.
Keywords: chx; antimicrobial susceptibility; activated sludge; chlorhexidine ... See more keywords
Hypersensitivity reaction of the gingiva to chlorhexidine: case report and literature review.
Sign Up to like & getrecommendations! Published in 2020 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2020.04.814
Abstract: OBJECTIVE The aim of this case report was to document a case of delayed-type hypersensitivity reaction of the gingiva to chlorhexidine and review the literature on oral mucosal hypersensitivity reactions associated to chlorhexidine-containing oral hygiene… read more here.
Keywords: literature; hypersensitivity reaction; case; chlorhexidine ... See more keywords
Does a diluted chlorhexidine-based orthodontic mouthwash cause less discoloration compared to chlorhexidine mouthwash in fixed orthodontic patients? A randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2021 at "International orthodontics"
DOI: 10.1016/j.ortho.2021.05.001
Abstract: OBJECTIVE Chlorhexidine gluconate is currently the most effective oral antimicrobial agent against microorganisms, but discoloration of the teeth prevents its long-term use and can reduce patient cooperation. In this study, the effect of chlorhexidine and… read more here.
Keywords: stain; orthodontic patients; fixed orthodontic; discoloration ... See more keywords
Long-term antibacterial and stable chlorhexidine-polydopamine coating on stainless steel 316L
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Organic Coatings"
DOI: 10.1016/j.porgcoat.2018.05.012
Abstract: Abstract Immobilization of chlorhexidine (CHX) coating on medical devices by utilizing a polydopamine (PDA) film as an intermediate crosslinker, demonstrates a promising value in retarding bacterial growth. However, its long-term antibacterial effect and coating stability… read more here.
Keywords: long term; chx; term antibacterial; polydopamine ... See more keywords
In vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00140
Abstract: Keratitis is a severe, sight threatening condition caused by microbial infection. Eyedrops are the standard delivery medium for treating these disorders; however, blinking, elevated tear production and nasolacrimal drainage eliminates much of the instilled dose… read more here.
Keywords: drug loaded; delivery; drug; chlorhexidine ... See more keywords
Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst forms
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DOI: 10.1038/s41598-021-87381-x
Abstract: Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma. The combination of chlorhexidine and propamidine isethionate… read more here.
Keywords: garcinia mangostana; mangostin acanthamoeba; extract mangostin; chlorhexidine ... See more keywords
Two birds with one stone: natural polyphenols boosted periodontitis treatment of chlorhexidine via reducing toxicity and regulating microenvironments.
Sign Up to like & getrecommendations! Published in 2024 at "Materials horizons"
DOI: 10.1039/d4mh01137f
Abstract: Chlorhexidine (CHX) is considered the gold standard for controlling periodontal plaque and has been extensively used as a topical agent in treating periodontitis. Nevertheless, the practical clinical application of CHX is still constrained by the… read more here.
Keywords: chx; periodontitis; egcg chx; toxicity ... See more keywords