Double-edged GABAergic synaptic transmission in seizures: The importance of chloride plasticity
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DOI: 10.1016/j.brainres.2018.09.008
Abstract: GABAergic synaptic inhibition, which is a critical regulator of neuronal excitability, is closely involved in epilepsy. Interestingly, fast GABAergic transmission mediated by Cl- permeable GABAA receptors can bi-directionally exert both seizure-suppressing and seizure-promoting actions. Accumulating… read more here.
Keywords: synaptic transmission; gabaergic synaptic; chloride plasticity; pathology ... See more keywords