Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis.
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DOI: 10.1021/acs.jmedchem.2c00511
Abstract: Misfolding and aggregation of transthyretin are implicated in the fatal systemic disease known as transthyretin amyloidosis. Here, we report the development of a naringenin derivative bearing two chlorine atoms that will be efficacious for preventing… read more here.
Keywords: chlorinated naringenin; transthyretin; analogues potential; potential inhibitors ... See more keywords