p-Chloro-diphenyl diselenide attenuates plasma lipid profile changes and hepatotoxicity induced by nonionic surfactant tyloxapol in rats
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2019.1669240
Abstract: Abstract Tyloxapol is a nonionic surfactant oligomer inductor of dyslipidemia, which in turn is a risk factor for liver damage. Selenium-based compounds have emerged as promising therapeutic candidates for treating different experimental disorders. This study… read more here.
Keywords: chloro diphenyl; diphenyl diselenide; tyloxapol; plasma lipid ... See more keywords
p-Chloro-diphenyl diselenide modulates Nrf2/Keap1 signaling and counteracts renal oxidative stress in mice exposed to dexamethasone repeated administrations.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2021-0573
Abstract: Dexamethasone is a synthetic glucocorticoid that has been associated with oxidative stress in central and peripheral tissues. p-Chloro-diphenyl diselenide (p-ClPhSe)2 is an antioxidant organoselenium compound. The present study aimed to evaluate whether Nrf2/Keap-1 signaling contributes… read more here.
Keywords: diphenyl diselenide; mice exposed; oxidative stress; exposed dexamethasone ... See more keywords