In vitro and in vivo assessments of the genotoxic potential of 3‐chloroallyl alcohol
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22515
Abstract: 3‐Chloroallyl alcohol (3‐CAA) can be found in the environment following the application of plant protection products. 3‐CAA is formed in groundwater following the injection of 1,3‐dichloropropene, a fumigant used to control nematodes. 3‐CAA is also… read more here.
Keywords: vitro vivo; caa; chloroallyl alcohol;
PBPK modeling to evaluate maximum tolerated doses: A case study with 3-chloroallyl alcohol
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1088011
Abstract: Introduction: A physiologically based pharmacokinetic (PBPK) model for 3-chloroallyl alcohol (3-CAA) was developed and used to evaluate the design of assays for the in vivo genotoxicity of 3-CAA. Methods: Model development was supported by read… read more here.
Keywords: pbpk modeling; pbpk model; model; alcohol ... See more keywords