Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium.
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DOI: 10.1038/nchem.2746
Abstract: Difluoromethylated aromatic compounds are of increasing importance in pharmaceuticals, agrochemicals and materials. Chlorodifluoromethane (ClCF2H), an inexpensive, abundant and widely used industrial raw material, represents the ideal and most straightforward difluoromethylating reagent, but introduction of the… read more here.
Keywords: triggered formation; difluoromethylated arenes; chlorodifluoromethane triggered; metal difluorocarbene ... See more keywords