Pathological Features of Corneal Phospholipidosis in Juvenile White Rabbits Induced by Ocular Instillation of Chloroquine or Amiodarone
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DOI: 10.1177/0192623318809000
Abstract: Cationic amphiphilic drugs (CADs) can induce phospholipidosis (PLD) in organs/tissues. Several ophthalmic pharmaceuticals containing CADs are marketed and used in children. To investigate the effect of PLD on the developing cornea, chloroquine and amiodarone, which… read more here.
Keywords: young adult; amiodarone; chloroquine amiodarone; adult rabbits ... See more keywords
Characteristics of corneal phospholipidosis induced by topical ocular application of chloroquine and amiodarone in rabbits
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DOI: 10.1293/tox.2016-0003
Abstract: Several cationic-amphiphilic drugs such as chloroquine and amiodarone are known to induce phospholipidosis in the cornea by systemic administration. However, the characteristics of ophthalmological and pathological changes when phospholipidosis-inducing drugs are topically applied have not… read more here.
Keywords: microscopy; chloroquine amiodarone; phospholipidosis; characteristics corneal ... See more keywords