Progressive increase in point mutations associates chloroquine resistance: Even after withdrawal of chloroquine use in India
Sign Up to like & getrecommendations! Published in 2017 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2017.06.002
Abstract: Chloroquine (CQ) is highly effective against P. vivax, due to the rapid spread of CQ resistance in P. falciparum parasites; it is no longer the drug of choice against P. falciparum. This study elucidates the… read more here.
Keywords: yysny; chloroquine resistance; resistance; withdrawal chloroquine ... See more keywords
The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01101-22
Abstract: The chloroquine resistance transporter, PfCRT, is important for the survival of the human malaria parasite Plasmodium falciparum. It increases the tolerance to many antimalarial drugs, and it is essential for the development of the parasite… read more here.
Keywords: chloroquine resistance; falciparum; resistance; pfcrt ... See more keywords
Cross sectional study to determine chloroquine resistance among Plasmodium falciparum clinical isolates from Khartoum, Sudan
Sign Up to like & getrecommendations! Published in 2018 at "F1000Research"
DOI: 10.12688/f1000research.13273.1
Abstract: Background: Malaria continues to present a global health threat; the World Health Organization (WHO) reported 214 million cases of malaria by the year 2015 with a death rate of 438000. Sudan is endemic to malaria… read more here.
Keywords: malaria; treatment; chloroquine resistance; plasmodium falciparum ... See more keywords
No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti
Sign Up to like & getrecommendations! Published in 2018 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2411.180738
Abstract: We obtained 78 human blood samples from areas in Haiti with high transmission of malaria and found no drug resistance–associated mutations in Plasmodium falciparum chloroquine resistance transporter and Kelch 13 genes. We recommend maintaining chloroquine… read more here.
Keywords: falciparum chloroquine; resistance transporter; chloroquine resistance; plasmodium falciparum ... See more keywords
Short-Time Recurrences of Plasmodium vivax Malaria as a Public Health Proxy for Chloroquine-Resistance Surveillance: A Spatio-Temporal Study in the Brazilian Amazon
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph18105061
Abstract: In Brazil, malaria caused by Plasmodium vivax presents control challenges due to several reasons, among them the increasing possibility of failure of P. vivax treatment due to chloroquine-resistance (CQR). Despite limited reports of CQR, more… read more here.
Keywords: chloroquine resistance; plasmodium vivax; short time; time recurrences ... See more keywords