Synthesis of Novel 2- and 8-Substituted 4-Amino-7-chloroquinolines and their N-Alkylated Coupling Products
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DOI: 10.1139/cjc-2023-0005
Abstract: The synthesis of a series of 2- and 8-substituted 4-amino-7-chloroquinolines is presented. The chloro in the 7-position can be effectively substituted using amino alcohols to yield novel analogues of the antimalarial (hydroxy)chloroquine. Both short chain… read more here.
Keywords: chloroquinolines alkylated; substituted amino; novel substituted; amino chloroquinolines ... See more keywords