Cyclodextrin complexation studies as the first step for repurposing of chlorpromazine.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119391
Abstract: The antipsychotic drug chlorpromazine (CPZ) has potential for the treatment of acute myeloid leukemia, if central nervous system side-effects resulting from its passage through the blood-brain barrier can be prevented. A robust drug delivery system… read more here.
Keywords: chlorpromazine; complexation; drug; cyclodextrin complexation ... See more keywords
Observation of Clinical Efficacy of Anisodamine and Chlorpromazine in the Treatment of Intractable Hiccup after Stroke
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/6563193
Abstract: Objective This study is aimed at investigating the clinical efficacy of anisodamine combined with chlorpromazine on intractable hiccups after stroke. Methods 150 patients admitted to Affiliated Hospital of the Hebei University of Engineering from 2017… read more here.
Keywords: chlorpromazine; anisodamine; group group; group ... See more keywords
Light-Induced Reactions of Chlorpromazine in the Presence of a Heterogeneous Photocatalyst: Formation of a Long-Lasting Sulfoxide
Sign Up to like & getrecommendations! Published in 2019 at "Catalysts"
DOI: 10.3390/catal9070627
Abstract: A commercial carbon-modified titanium dioxide, KRONOClean 7000, was applied as a UV(A) and visible-light active photocatalyst to investigate the conversion of the antipsychotic pharmaceutical chlorpromazine in aqueous phase employing two monochromatic light sources emitting at… read more here.
Keywords: photocatalyst; presence; chlorpromazine; conversion ... See more keywords
Inhibitory Effects of Antipsychotic Chlorpromazine on the Survival, Reproduction and Population Growth Other Than Neurotransmitters of Zooplankton in Light of Global Warming
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192316167
Abstract: Global warming and environmental pollution have created a unique combination of abiotic and biotic stresses to zooplankton. However, little information is available on the effects of antipsychotic drugs commonly used to treat psychosis, such as… read more here.
Keywords: chlorpromazine; light global; global warming; population growth ... See more keywords
Dynamic Changes in Plasma Metabolic Profiles Reveal a Potential Metabolite Panel for Interpretation of Fatal Intoxication by Chlorpromazine or Olanzapine in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12121184
Abstract: Diagnosing the cause of fatal intoxication by antipsychotic agents is an important task in forensic practice. In the 2020 Annual Report of the American Association of Poison Control Centers, among 40 deaths caused by antipsychotics,… read more here.
Keywords: metabolic profiles; chlorpromazine; fatal intoxication; olanzapine ... See more keywords
Pulsed Laser Photo-Crosslinking of Gelatin Methacryloyl Hydrogels for the Controlled Delivery of Chlorpromazine to Combat Antimicrobial Resistance
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102121
Abstract: Hydrogels are ideal candidates for the sustained local administration of antimicrobial drugs because they have customizable physicochemical properties that allow drug release kinetics to be controlled and potentially address the issue of systemic side effects.… read more here.
Keywords: chlorpromazine; spectroscopy; gelatin methacryloyl; methacryloyl hydrogels ... See more keywords
Clozapine‐induced maculopathy
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DOI: 10.5694/mja17.00452
Abstract: We acknowledge the dopamine hypothesis, but due to the constraints of the MJA snapshot format, this was not postulated or expanded on in our article. Clozapine is classified as a phenothiazine, which is a major… read more here.
Keywords: induced maculopathy; clozapine induced; chlorpromazine; pigmentation ... See more keywords