Chlorpromazine and promethazine reduces Brain injury through RIP1-RIP3 regulated activation of NLRP3 inflammasome following ischemic stroke
Sign Up to like & getrecommendations! Published in 2021 at "Neurological Research"
DOI: 10.1080/01616412.2021.1910904
Abstract: ABSTRACT Objectives: Stroke is an important cause of death and disability. Recent evidence suggests that post-stroke inflammation is an important factor in stroke pathology and a root cause of its lasting consequences. Phenothiazine drugs, like… read more here.
Keywords: ischemic stroke; rip3; chlorpromazine promethazine; rip1 rip3 ... See more keywords
Abstract WMP38: Acute Administration of Chlorpromazine and Promethazine Reduces Brain Apoptosis in Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/str.49.suppl_1.wmp38
Abstract: Introduction: In recent studies conducted by our lab, acute administration of chlorpromazine and promethazine (C+P) in ischemic stroke has been shown, through the induction of a metabolically-slowed, hibernation-like state, to reduce infarct size and neurological… read more here.
Keywords: ischemic stroke; acute administration; chlorpromazine promethazine; administration chlorpromazine ... See more keywords