Liver Injury in Uncomplicated Malaria is an Overlooked Phenomenon: An Observational Study
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.09.018
Abstract: Abstract Background Liver injury is a known feature of severe malaria, but is only incidentally investigated in uncomplicated disease. In such cases, drug-induced hepatotoxicity is often thought to be the primary cause of the observed… read more here.
Keywords: study; chmi; uncomplicated malaria; lft abnormalities ... See more keywords
Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
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DOI: 10.1186/s12879-022-07044-8
Abstract: Background Individuals living in endemic areas acquire immunity to malaria following repeated parasite exposure. We sought to assess the controlled human malaria infection (CHMI) model as a means of studying naturally acquired immunity in Kenyan… read more here.
Keywords: chmi; exposure; immunity; malaria ... See more keywords
Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.984323
Abstract: In endemic settings it is known that natural malaria immunity is gradually acquired following repeated exposures. Here we sought to assess whether similar acquisition of blood-stage malaria immunity would occur following repeated parasite exposure by… read more here.
Keywords: infection; blood stage; malaria; chmi ... See more keywords