SIRT6 Protects Against Myocardial Ischemia–Reperfusion Injury by Attenuating Aging-Related CHMP2B Accumulation
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DOI: 10.1007/s12265-021-10184-y
Abstract: Impaired autophagic flux induces aging-related ischemia vulnerability, which is the hallmark pathology in cardiac aging. Our previous work has confirmed that the accumulation of charged multivesicular body protein 2B (CHMP2B), a subunit of the ESCRT-III… read more here.
Keywords: ischemia; accumulation; chmp2b accumulation; aging related ... See more keywords