N123I mutation in the ALV-J receptor-binding domain region enhances viral replication ability by increasing the binding affinity with chNHE1
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011928
Abstract: The subgroup J avian leukosis virus (ALV-J), a retrovirus, uses its gp85 protein to bind to the receptor, the chicken sodium hydrogen exchanger isoform 1 (chNHE1), facilitating viral invasion. ALV-J is the main epidemic subgroup… read more here.
Keywords: replication; chnhe1; viral replication; alv ... See more keywords