Antibody glycation during a CHO fed-batch process following a constrained second order reaction.
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DOI: 10.1002/btpr.3261
Abstract: Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well-known phenomenon in manufacturing processes of biopharmaceuticals that potentially alter the efficacy of the therapeutic protein. In the present study, we report kinetic… read more here.
Keywords: cho fed; fed batch; order; reaction ... See more keywords