Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines.
Sign Up to like & getrecommendations! Published in 2019 at "Drug metabolism letters"
DOI: 10.2174/1872312813666181129101507
Abstract: BACKGROUND Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobupropion (TB). At present, the mechanisms underlying the… read more here.
Keywords: bup; hek293 cell; cell lines; hek293 ... See more keywords
Predicting Transiently Expressed Protein Yields: Comparison of Transfection Methods in CHO and HEK293
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14091949
Abstract: Therapeutic proteins are currently at the apex of innovation in pharmaceutical medicine. However, their industrial production is technically challenging and improved methods for transient transfection of mammalian cell cultures are necessary. We aimed to find… read more here.
Keywords: cell; protein yields; cho hek293; transfection ... See more keywords