Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages
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DOI: 10.1002/bit.28036
Abstract: In this study, we examined DNA methylation and transcription profiles of recombinant clones derived from two different Chinese hamster ovary hosts. We found striking epigenetic differences between the clones, with global hypomethylation in the host… read more here.
Keywords: epigenetic comparison; methylation; transcription; comparison cho ... See more keywords