Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.
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DOI: 10.1016/j.biomaterials.2019.01.023
Abstract: There has been a progressive interest in the molecular design of polymers and lipids as synthetic carriers for targeting therapeutic mRNA in vivo with the ability to circumvent nuclease attack for treating intractable diseases. Herein,… read more here.
Keywords: rna oligonucleotides; chol oligorna; polyplex micelles; cholesteryl ... See more keywords