TRIM29 facilitates proliferation and malignancy of cholangiocarcinoma cells by activating MAPK and β-catenin pathways.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23826
Abstract: BACKGROUND Tripartite motif-containing 29 (TRIM29) has been found to be involved in the regulation of cancer progression and its function varies depending on the type of cancer. However, the role of TRIM29 in cholangiocarcinoma has… read more here.
Keywords: cholangiocarcinoma cells; trim29; proliferation; cholangiocarcinoma ... See more keywords
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.12.070
Abstract: Photodynamic therapy (PDT) provides apparent survival benefits for unresectable cholangiocarcinoma patients. the insufficient sensitivity of cancer cell to PDT treatment limits the clinical application. In this study, according to the GEO datasets, WNT7B expression was… read more here.
Keywords: p53; cholangiocarcinoma cells; cholangiocarcinoma; pdt treatment ... See more keywords
UCP2 regulates cholangiocarcinoma cell plasticity via mitochondria-to-AMPK signals.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.05.017
Abstract: Uncoupling protein 2 (UCP2) is upregulated in several human cancers which contributes to tumorigenesis. However, whether UCP2 expression is amplified in cholangiocarcinoma and whether UCP2 promotes cholangiocarcinoma progression are not known. Our results found that… read more here.
Keywords: ucp2 expression; cholangiocarcinoma cells; ucp2 regulates; cholangiocarcinoma ... See more keywords
Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98948-z
Abstract: In the present study, we aimed to find the target of Tanshinone IIA (Tan-IIA) in Cholangiocarcinoma by network pharmacology-based prediction and investigate the possible mechanism through experimental verification. In this study, we combined Tan-IIA-specific and… read more here.
Keywords: tan iia; cholangiocarcinoma cells; pharmacology; mtor ... See more keywords
Automated selection of aptamers against cholangiocarcinoma cells on an integrated microfluidic platform.
Sign Up to like & getrecommendations! Published in 2017 at "Biomicrofluidics"
DOI: 10.1063/1.4991005
Abstract: An integrated microfluidic system capable of automatically identifying aptamers specific to cholangiocarcinoma (CCA) cells was developed herein. The developed system was capable of performing cell-based systematic evolution of ligands via an exponential enrichment (Cell-SELEX) process… read more here.
Keywords: aptamers cholangiocarcinoma; cholangiocarcinoma cells; integrated microfluidic; automated selection ... See more keywords
Flavokawain B Inhibits Growth of Cholangiocarcinoma Cells by Suppressing the Akt Pathway
Sign Up to like & getrecommendations! Published in 2023 at "In Vivo"
DOI: 10.21873/invivo.13182
Abstract: Background/Aim: Cholangiocarcinoma is a devastating malignancy with limited treatment options and poor prognosis. Natural products have gained considerable attention for showing antitumor effects with less toxicities. Flavokawain B (FKB), a natural product, has been studied… read more here.
Keywords: effect fkb; cholangiocarcinoma cells; fkb; akt pathway ... See more keywords
A Study on Mesoporous Silica Loaded With Novel Photosensitizers HCE6 and Oxaliplatin for the Treatment of Cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.665182
Abstract: Purpose Cholangiocarcinoma (CCA) is a malignant tumor with a high incidence. The therapeutic effect of conventional chemotherapy and radiotherapy is not obvious. Photodynamic therapy (PDT) is an ideal modality to fight cancer, and the nature… read more here.
Keywords: msns; cholangiocarcinoma cells; mesoporous silica; study mesoporous ... See more keywords
Intrahepatic Cholangiocarcinoma Cells Promote Epithelial-mesenchymal Transition of Hepatocellular Carcinoma Cells by Secreting LAMC2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.55627
Abstract: Hepatocellular carcinoma and intrahepatic cholangiocarcinoma cells are common primary hepatic tumor cells in the liver. Combined hepatocellular cholangiocarcinoma (CHC) contains both hepatocellular carcinoma cells and intrahepatic cholangiocarcinoma cells in one tumor lesion and these tumors… read more here.
Keywords: hepatocellular carcinoma; cholangiocarcinoma cells; intrahepatic cholangiocarcinoma; cholangiocarcinoma ... See more keywords