Cholangiocyte‐derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans
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DOI: 10.1002/hep.29838
Abstract: Cholestatic liver injury is an important clinical problem with limited understanding of disease pathologies. Exosomes are small extracellular vesicles released by a variety of cells, including cholangiocytes. Exosome‐mediated cell‐cell communication can modulate various cellular functions… read more here.
Keywords: cholestatic liver; hepatology; cholangiocyte derived; liver injury ... See more keywords
Cholangiocyte‐Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis
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DOI: 10.1002/hep.30662
Abstract: Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte‐derived exosomal long noncoding RNA‐H19 (lncRNA‐H19) plays a critical role in… read more here.
Keywords: liver fibrosis; liver; cholangiocyte derived; activation ... See more keywords