The ascending pathophysiology of cholestatic liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28965
Abstract: In this review we develop the argument that cholestatic liver diseases, particularly primary biliary cholangitis and primary sclerosing cholangitis (PSC), evolve over time with anatomically an ascending course of the disease process. The first and… read more here.
Keywords: cholestatic liver; disease; liver; pathophysiology ... See more keywords
Mechanisms and molecules: What are the treatment targets for primary biliary cholangitis?
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32405
Abstract: Treatment of primary biliary cholangitis (PBC) with ursodeoxycholic acid (UDCA) is not always sufficient to prevent progression to hepatic decompensation and/or need for liver transplant. Adjuvant therapy with obeticholic acid may provide additional biochemical improvements… read more here.
Keywords: cell; mechanisms molecules; primary biliary; biliary cholangitis ... See more keywords
Doppler ultrasonography blood flow changes of the hepatic artery in liver transplants complicated with cholangitis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23466
Abstract: Cholangitis after liver transplantation may lead to bile duct necrosis. Early diagnosis is essential to prevent graft loss. We aimed to investigate cholangitis related hepatic arterial Doppler ultrasonography findings in liver transplants. read more here.
Keywords: cholangitis; ultrasonography blood; doppler ultrasonography; liver transplants ... See more keywords
Primär biliäre Cholangitis – etablierte und neue Therapien
Sign Up to like & getrecommendations! Published in 2018 at "Der Internist"
DOI: 10.1007/s00108-018-0427-0
Abstract: ZusammenfassungHintergrundPatienten mit primär biliärer Cholangitis (PBC, vormals primär biliäre Zirrhose) und unzureichendem Therapieansprechen oder Risikofaktoren haben ein deutlich erhöhtes Risiko, dass die Erkrankung bis zur Leberzirrhose und deren Komplikationen fortschreitet. Ferner ist die Lebensqualität zahlreicher… read more here.
Keywords: die; pbc; cholangitis; prim bili ... See more keywords
IgG4-assoziierte Cholangitis – klinische Präsentation eines lange übersehenen Krankheitsbildes
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DOI: 10.1007/s00108-018-0431-4
Abstract: ZusammenfassungDie Immunglobulin-G4-assoziierte Cholangitis (IAC) ist die hepatobiliäre Manifestation der IgG4-assoziierten Erkrankung, einer autoimmunvermittelten entzündlich-fibrosierenden Systemerkrankung, die mit zumeist erhöhtem IgG4-Serumspiegel und typischen histopathologischen Veränderungen in den betroffenen Organen einhergeht. Die IAC tritt in über 90 %… read more here.
Keywords: manifestation; igg4; die; cholangitis ... See more keywords
Chronisch-entzündliche Lebererkrankungen
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DOI: 10.1007/s00108-018-0433-2
Abstract: Chronische Leberentzündungen sind ätiologisch heterogene Krankheitsbilder, die über die chronische Hepatitis zur Leberzirrhose und deren Komplikationen einschließlich des hepatozellulären Karzinoms führen können. Die Dekompensation einer Leberzirrhose und die Entwicklung eines Leberzellkarzinoms können Tod oder Transplantation… read more here.
Keywords: die; ndungen; chronischen; cholangitis ... See more keywords
Does measurement of the hepatic artery velocity improve the sonographic diagnosis of cholangitis?
Sign Up to like & getrecommendations! Published in 2019 at "Abdominal Radiology"
DOI: 10.1007/s00261-019-02284-w
Abstract: To determine the frequency of elevated peak systolic proper hepatic artery velocity (HAV) in patients with acute cholangitis and to determine the diagnostic performance of this metric relative to existing criteria. Between 9/2016 and 11/2017,… read more here.
Keywords: hav; artery velocity; elevated hav; cholangitis ... See more keywords
Missing duct sign
Sign Up to like & getrecommendations! Published in 2020 at "Abdominal Radiology"
DOI: 10.1007/s00261-019-02397-2
Abstract: Missing duct sign is produced when an intrahepatic stone completely obstructs the orifice of a segmental or subsegmental bile duct on cholangiogram in recurrent pyogenic cholangitis [1] (Figs. 1, 2). In an opacified biliary tree,… read more here.
Keywords: missing duct; recurrent pyogenic; cholangitis; duct sign ... See more keywords
Mimics of cholangiocarcinoma–exploring beneath the surface!
Sign Up to like & getrecommendations! Published in 2022 at "Abdominal Radiology"
DOI: 10.1007/s00261-022-03459-8
Abstract: We read with interest the pictorial review on mimics of cholangiocarcinoma recently published in Abdominal Radiology [1]. At the outset, we congratulate the authors for showing a nice spectrum of both benign and malignant differential… read more here.
Keywords: cholangitis; radiology; mimics cholangiocarcinoma; cholangiocarcinoma ... See more keywords
Immune-mediated cholangitis: is it always nivolumab’s fault?
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-018-2159-3
Abstract: We read with much interest the article published by Kashima and colleagues on “Bile duct obstruction in a patient treated with nivolumab as second-line chemotherapy for advanced non-small cell lung cancer: a case report” [1].… read more here.
Keywords: disease; case; related cholangitis; cholangitis ... See more keywords
Impact of infected stent removal on recurrent cholangitis with time-to-event analysis
Sign Up to like & getrecommendations! Published in 2019 at "Surgical Endoscopy"
DOI: 10.1007/s00464-019-06714-0
Abstract: BackgroundThe optimal approach at treating infected biliary stents at the time of cholangitis remains unknown. This study aims to compare the efficacy of stent exchange versus stent sweeping/stent-in-stent approaches at treating cholangitis.MethodsThe study was a… read more here.
Keywords: recurrent cholangitis; cholangitis; stent removal;