The effect of Crocin on TFAM and PGC-1Ī± expression and Catalase and Superoxide dismutase activities following cholestasis-induced neuroinflammation in the striatum of male Wistar rats.
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DOI: 10.1007/s11011-021-00748-x
Abstract: Bile secretion is a physiological function that is disrupted following Bile Duct Ligation (BDL) and induces cholestasis. Cholestasis is a bile flow reduction that induces apoptosis, oxidative stress, and inflammation, and alters the expression of… read more here.
Keywords: tfam pgc; neuroinflammation; pgc; crocin ... See more keywords
Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns
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DOI: 10.1080/19490976.2021.1911534
Abstract: ABSTRACT Intestinal microbiota regulates multiple host metabolic and immunological processes. Consequently, any difference in its qualitative and quantitative composition is susceptible to exert significant effects, in particular along the gut-liver axis. Indeed, recent findings suggest… read more here.
Keywords: gene expression; intestinal microbiota; microbiota; cholestasis induced ... See more keywords
Novel mouse model for cholestasisāinduced liver fibrosis resolution by cholecystojejunostomy
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DOI: 10.1111/jgh.15406
Abstract: Studies on the resolution of liver fibrosis are becoming more important in this era of etiologic eradication. In contrast to the extensive research on the recovery of liver fibrosis induced by hepatotoxic injuries, regression of… read more here.
Keywords: model cholestasis; novel mouse; fibrosis; liver fibrosis ... See more keywords