Preparation, Determination of Activity, and Biodistribution of Cholesterol-Containing Nuclease-Resistant siRNAs In Vivo.
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DOI: 10.1007/978-1-0716-0290-4_3
Abstract: RNA interference (RNAi) is a powerful tool for suppressing gene expression associated with various diseases that are not amenable to treatment with low molecular weight drugs. Despite significant progress in this area, the potential for… read more here.
Keywords: determination activity; cholesterol containing; vivo; preparation determination ... See more keywords
Phase Heterogeneity in Cholesterol-Containing Ternary Phospholipid Lamellar Phases
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DOI: 10.1021/acsomega.2c04914
Abstract: Pseudo-ternary mixtures of lamellar phase phospholipids (DPPC and brain sphingomyelin with cholesterol) were studied below Tm, while comparing the influence of cholesterol content, temperature and the presence of small quantities of Vitamin D binding protein… read more here.
Keywords: containing ternary; ternary phospholipid; heterogeneity cholesterol; cholesterol containing ... See more keywords
Dynamic assembly and interaction of glycosphingolipids in cholesterol-containing model membranes
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DOI: 10.1515/pac-2023-0204
Abstract: Abstract Glycosphingolipids (GSLs) in the mammalian plasma membrane are essential for various biological events that occur on cell membranes by forming glycolipid-rich membrane domains, such as lipid rafts. Lactosylceramide (LacCer) forms a highly ordered phase… read more here.
Keywords: interaction; laccer; cholesterol containing; dynamic assembly ... See more keywords