Loading of cell cultures with cholesterol-dextran particles as a new functional test for Niemann-Pick type C disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inherited metabolic disease"
DOI: 10.1002/jimd.12481
Abstract: Deuterium-labeled cholesterol-dextran particles (d4-CholDex), prepared by co-precipitation, were internalized by cultured human skin fibroblasts and HEK293 cells. Subcellular particles from d4-CholDex-treated HEK293 cells were fractionated on iodixanol gradients. More than 60% of d4-cholesterol (d4-UC) in… read more here.
Keywords: cholesterol dextran; choldex; mean range; dextran particles ... See more keywords