Concentration-Dependent Effects of Cholesterol on the Dimerization of Amyloid-β Peptides in Lipid Bilayers.
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DOI: 10.1021/acschemneuro.2c00349
Abstract: Membrane disruption mediated by the accumulation of amyloid-β (Aβ) on cell membranes is central to the pathogenesis of Alzheimer's disease (AD). Cholesterol, an important component of membranes, is well-recognized as a risk factor in AD.… read more here.
Keywords: amyloid; effects cholesterol; dimerization; membrane ... See more keywords